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Grey's Anatomy S05E16, An Honest MistakeS05E16

Grey's Anatomy · Season 5

Grey's Anatomy season 5 episode 16: An Honest Mistake

Aired 19 February 200943 minRated TV-14

8.4TMDB · 16 votesMark watched

Where to watch Grey's Anatomy Season 5 in Australia

Grey's Anatomy season 5 is streaming in Australia on Disney+ (subscription, listed for the whole show).

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Stream (subscription)

Availability checked 16 November 2026.

What happens in “An Honest Mistake”

Derek's confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief's less-than-stellar recommendation letter.

Episode summary: TMDB.

Before you watch

  • It is episode 16 of 24 of season 5, so watch episodes 1 to 15 first.
  • It runs about 43 minutes.
  • Directed by Randall Zisk, written by Peter Nowalk.
  • TMDB users rate it 8.4 out of 10 (16 votes).

Grey's Anatomy trailer

The official trailer for the series (no preview of this episode has been published).

Grey's Anatomy trailerPlay video: Grey's Anatomy trailer

Cast and crew of this episode

Director
Randall Zisk
Writer
Peter Nowalk
Guest stars
Jessica Capshaw as Arizona RobbinsKate Walsh as Addison MontgomeryGloria Garayua as Intern GraciellaMark Saul as SteveFaye Dunaway as Dr. Margaret CampbellLouis Giambalvo as John TerzianJennifer Westfeldt as Jen HarmonBen Shenkman as Rob Harmon

Credits: TMDB.

More from Grey's Anatomy Season 5

Previous · S05E15Before and After12 February 2009Next · S05E17I Will Follow You Into the Dark12 March 2009
  1. E01
  2. E02
  3. E03
  4. E04
  5. E05
  6. E06
  7. E07
  8. E08
  9. E09
  10. E10
  11. E11
  12. E12
  13. E13
  14. E14
  15. E15
  16. E16
  17. E17
  18. E18
  19. E19
  20. E20
  21. E21
  22. E22
  23. E23
  24. E24

Every episode of Season 5Grey's Anatomy episode guide

Episode names, air dates, runtimes, stills and ratings: TMDB. Air dates are the first broadcast anywhere; where it streams is our daily Australian check.