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Grey's Anatomy S21E05, You Make My Heart ExplodeS21E05

Grey's Anatomy · Season 21

Grey's Anatomy season 21 episode 5: You Make My Heart Explode

Aired 24 October 202444 minRated TV-14

8.2TMDB · 8 votesMark watched

Where to watch Grey's Anatomy Season 21 in Australia

Grey's Anatomy season 21 is streaming in Australia on Disney+ (subscription, listed for the whole show).

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Stream (subscription)

Availability checked 16 November 2026.

What happens in “You Make My Heart Explode”

During a high-stress day at Grey Sloan Memorial, the fates of a patient in critical condition and a helicopter-bound medical team hang in the balance. Teddy and Owen work on their marriage, while Bailey, Blue and Link treat a hospital employee.

Episode summary: TMDB.

Before you watch

  • It is episode 5 of 18 of season 21, so watch episodes 1 to 4 first.
  • It runs about 44 minutes.
  • Directed by Vanessa Parise, written by Zoanne Clack.
  • TMDB users rate it 8.2 out of 10 (8 votes).

Grey's Anatomy trailer

The official trailer for the series (no preview of this episode has been published).

Grey's Anatomy trailerPlay video: Grey's Anatomy trailer

Cast and crew of this episode

Director
Vanessa Parise
Writer
Zoanne Clack
Guest stars
Jake Borelli as Levi SchmittNatalie Morales as Monica BeltranJoAnna Rhambo as NurseMichael Thomas Grant as James MorganTroy Winbush as Darren RileyJohn Posey as Aurelio WheelerJustiin Davis as Zane JohnsonJohnny Pacar as Dr. Manuel Tyson

Credits: TMDB.

More from Grey's Anatomy Season 21

  1. E01
  2. E02
  3. E03
  4. E04
  5. E05
  6. E06
  7. E07
  8. E08
  9. E09
  10. E10
  11. E11
  12. E12
  13. E13
  14. E14
  15. E15
  16. E16
  17. E17
  18. E18

Every episode of Season 21Grey's Anatomy episode guide

Episode names, air dates, runtimes, stills and ratings: TMDB. Air dates are the first broadcast anywhere; where it streams is our daily Australian check.