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Grey's Anatomy S21E01, If Walls Could TalkS21E01

Grey's Anatomy · Season 21

Grey's Anatomy season 21 episode 1: If Walls Could Talk

Aired 26 September 202444 minRated TV-14

8.5TMDB · 10 votesMark watched

Where to watch Grey's Anatomy Season 21 in Australia

Grey's Anatomy season 21 is streaming in Australia on Disney+ (subscription, listed for the whole show).

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Stream (subscription)

Availability checked 16 November 2026.

What happens in “If Walls Could Talk”

After firing some of Grey Sloan's best, Catherine continues to interfere with Meredith and Amelia's research. Accidents at a climate change protest bring unique cases to the hospital, and Bailey encounters a blast from the past.

Episode summary: TMDB.

Before you watch

  • It is the season premiere of season 21.
  • It runs about 44 minutes.
  • Directed by Debbie Allen, written by Meg Marinis.
  • TMDB users rate it 8.5 out of 10 (10 votes).

Grey's Anatomy trailer

The official trailer for the series (no preview of this episode has been published).

Grey's Anatomy trailerPlay video: Grey's Anatomy trailer

Cast and crew of this episode

Director
Debbie Allen
Writer
Meg Marinis
Guest stars
Jesse Williams as Jackson AveryJake Borelli as Levi SchmittMidori Francis as Mika YasudaKali Rocha as Sydney HeronDebbie Allen as Catherine FoxDianne Doan as Molly TranAntonio Raul Garcia as IanAshton Moio as Charlie Scott

Credits: TMDB.

More from Grey's Anatomy Season 21

  1. E01
  2. E02
  3. E03
  4. E04
  5. E05
  6. E06
  7. E07
  8. E08
  9. E09
  10. E10
  11. E11
  12. E12
  13. E13
  14. E14
  15. E15
  16. E16
  17. E17
  18. E18

Every episode of Season 21Grey's Anatomy episode guide

Episode names, air dates, runtimes, stills and ratings: TMDB. Air dates are the first broadcast anywhere; where it streams is our daily Australian check.