S03E21Grey's Anatomy season 3 episode 21: Desire
Aired 26 April 200743 minRated TV-14
Where to watch Grey's Anatomy Season 3 in Australia
Grey's Anatomy season 3 is streaming in Australia on Disney+ (subscription, listed for the whole show).
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Availability checked 16 November 2026.
What happens in “Desire”
The attendings vie to be Chief. Two people who haven't slept together before, will. McSteamy's 60-day vow of chastity has a conclusion. We meet a boss, his assistant, and his wife. We also get to see someone being treated in the clinic. Derek has more questions about his relationship with Meredith. The chairman of the hospital board is admitted as patient. Callie confronts Izzie about her relationship with George.
Episode summary: TMDB.
Before you watch
- It is episode 21 of 24 of season 3, so watch episodes 1 to 20 first.
- It runs about 43 minutes.
- Directed by Tom Verica, written by Mark Wilding.
- TMDB users rate it 8.3 out of 10 (16 votes).
Grey's Anatomy trailer
The official trailer for the series (no preview of this episode has been published).
Play video: Grey's Anatomy trailer
Cast and crew of this episode
- Director
- Tom Verica
- Writer
- Mark Wilding
- Guest stars
- Mitch Pileggi as Lawrence JenningsRowena King as Celeste NewmanMary-Margaret Humes as Nancy JenningsKali Rocha as Sydney HeronElizabeth Reaser as Jane Doe / AvaRamon De Ocampo as James BentonStewart Skelton as Dr. Fischer
Credits: TMDB.
More from Grey's Anatomy Season 3
Every episode of Season 3Grey's Anatomy episode guide
Episode names, air dates, runtimes, stills and ratings: TMDB. Air dates are the first broadcast anywhere; where it streams is our daily Australian check.