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Grey's Anatomy S10E21, Change of HeartS10E21

Grey's Anatomy · Season 10

Grey's Anatomy season 10 episode 21: Change of Heart

Aired 24 April 201443 minRated TV-14

8.5TMDB · 10 votesMark watched

Where to watch Grey's Anatomy Season 10 in Australia

Grey's Anatomy season 10 is streaming in Australia on Disney+ (subscription, listed for the whole show).

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Stream (subscription)

Availability checked 16 November 2026.

What happens in “Change of Heart”

Jackson is given the daunting task of delivering disappointing news to the doctors. Meanwhile, Derek's sister Amelia drops by for a surprise visit, Richard surprises Catherine in Boston and when Bailey gets frustrated by the slow pace of her research, she makes a risky decision.

Episode summary: TMDB.

Before you watch

  • It is episode 21 of 24 of season 10, so watch episodes 1 to 20 first.
  • It runs about 43 minutes.
  • Directed by Rob J. Greenlea, written by Meg Marinis.
  • TMDB users rate it 8.5 out of 10 (10 votes).

Grey's Anatomy trailer

The official trailer for the series (no preview of this episode has been published).

Grey's Anatomy trailerPlay video: Grey's Anatomy trailer

Cast and crew of this episode

Director
Rob J. Greenlea
Writer
Meg Marinis
Guest stars
Caterina Scorsone as Amelia ShepherdDanny Nero as AnesthesiologistMark Adair-Rios as David MorrisRebecca Field as Sabine McNeilBilly Malone as Jon McNeilBresha Webb as Teresa MorrisJadin Gould as Ivy McNeilArmani Jackson as Braden Morris

Credits: TMDB.

More from Grey's Anatomy Season 10

Previous · S10E20Go It Alone17 April 2014Next · S10E22We Are Never Ever Getting Back Together1 May 2014
  1. E01
  2. E02
  3. E03
  4. E04
  5. E05
  6. E06
  7. E07
  8. E08
  9. E09
  10. E10
  11. E11
  12. E12
  13. E13
  14. E14
  15. E15
  16. E16
  17. E17
  18. E18
  19. E19
  20. E20
  21. E21
  22. E22
  23. E23
  24. E24

Every episode of Season 10Grey's Anatomy episode guide

Episode names, air dates, runtimes, stills and ratings: TMDB. Air dates are the first broadcast anywhere; where it streams is our daily Australian check.